a randomized clinical trial of group cognitive-rehabilitation therapy for patients with schizophrenia resistant to medication
نویسندگان
چکیده
objectives: against the background of evidence-based treatments for schizophrenia resistant to medication, the implementation of cognitive-rehabilitation therapy (crt) becomes more important, especially about patients who don’t response to medication. there is less evidence for group format and face to face structure of crt and also for resistant to medication patients. this research investigates the efficacy of gcrt decreasing positive and negative symptoms of schizophrenia and improving cognitive function. methods: a randomized controlled trial was used to compare the efficacy of gcrt that of patients who receive treatment as usual (tau). from razi hospital in tehran, 40 inpatient people with schizophrenia resistant to medication and persistent negative and positive symptoms were assigned. patients were included if they were aged 25 to 55 years had diagnosis of schizophrenia for at least 2 years and were persistent to medication for 2 years. 20 of them received a 16 session’s treatment over 2 months and 20other ones were in waiting list. all patients received tau throughout the study. in all, 40 completed treatment. the positive and negative symptoms scales, nosie & ncse completed for all patients before, in the middle and after treatment. results: spss 11.5 and multivariate repeated measure was used. there were significant differences between the gcbt and tau on positive and negative symptoms of schizophrenia. significant improvement were found in the severity and number of positive (p=0.05) and negative (p=0.001) symptoms in patients treated with gcrt. gcrt leaded to improvement in cognitive functions (p=0.001) but there was no change in behavioral functions. in control group there were no significant differences between three measures (pre, middle and post). discussion: gcrt is a useful adjunct therapy in the management of patients with schizophrenia resistant to medication in treating negative & positive symptoms as well as cognitive deficits.
منابع مشابه
A Randomized Clinical Trial of Group Cognitive-Rehabilitation Therapy for Patients with Schizophrenia Resistant to Medication
Objectives: Against the background of evidence-based treatments for schizophrenia resistant to medication, the implementation of cognitive-Rehabilitation therapy (CRT) becomes more important, especially about patients who don’t response to medication. There is less evidence for group format and face to face structure of CRT and also for resistant to medication patients. This research investigat...
متن کاملA randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication.
BACKGROUND Research evidence supports the efficacy of cognitive-behavioral therapy in the treatment of drug-refractory positive symptoms of schizophrenia. Although the cumulative evidence is strong, early controlled trials showed methodological limitations. METHODS A randomized controlled design was used to compare the efficacy of manualized cognitive-behavioral therapy developed particularly...
متن کاملLow Dose Celecoxib Combined with Clozapine for Treatment of Schizophrenia: A Double Blind Randomized Clinical Trial
Introduction: Higher levels of pro-inflammatory cytokines in schizophrenia have suggested that dysfunctions of the immune system may play a role in this disabling condition. The current study was performed to discover if low dose celecoxib combined with clozapine may improve symptoms of schizophrenia or not. Methods:<span...
متن کاملComparison of Two Manual Therapy Techniques in Patients with Carpal Tunnel Syndrome: A Randomized Clinical Trial
متن کامل
The Effect of Cognitive Behavior Therapy in Insomnia due to Methadone Maintenance Therapy: A Randomized Clinical Trial
Background: Sleep disturbance is a common complaint of patients undergoing methadone maintenance therapy (MMT). There are limited studies about the effect of different treatments on insomnia due to MMT. In this study, we evaluated the effect of cognitive-behavioral treatment for insomnia (CBTI) on sleep disorders in patients undergoing MMT.Methods: Twenty-two patients with insomnia due to MMT (...
متن کاملA randomized comparison of group cognitive-behavioural therapy and group psychoeducation in patients with schizophrenia.
OBJECTIVE Although the efficacy of cognitive-behavioural therapy (CBT) in schizophrenia has been established in a number of studies, no information is available on the differential efficacy of CBT in comparison with patient psychoeducation (PE). METHOD Eighty-eight in-patients with schizophrenia were randomized to receive a therapy envelope of 8 weeks including either 16 sessions group CBT or...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian rehabilitation journalجلد ۶، شماره ۱، صفحات ۵۹-۶۷
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023